BPC-157

BPC-157

BPC-157 Raw Material Technical Data Sheet

Product Name: BPC-157 Raw Material

CAS No.: 137525-51-0

Document Version: V1.0

Application: For Laboratory Research Only

Date: 2026


1. Basic Chemical Information

ItemSpecification
Full NameBPC-157 (Body Protection Compound 157, Pentadecapeptide)
SynonymBPA
Molecular FormulaC62H98N16O22
Molecular Weight1419.54 Da (free base)
1-Letter SequenceGEPPPGKPADDAGLV
3-Letter SequenceH-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH
Peptide Length15 amino acids, linear synthetic pentadecapeptide
Biological FunctionPromotes angiogenesis, cell migration, tissue regeneration, gastrointestinal mucosal protection, tendon & ligament repair, anti-inflammatory effect

2. Physical Characteristics

  • Appearance: White to off-white lyophilized powder
  • Odor: Odorless
  • Solubility: Freely soluble in sterile purified water / neutral PBS (pH 6.5–8.0); sparingly soluble in DMSO; insoluble in non-polar organic solvents
  • pH (1 mg/mL aqueous solution): 6.0 – 8.0
  • Hygroscopicity: Moderately hygroscopic; avoid long exposure to air and high humidity

3. Quality Specification

Test ItemTest MethodSpecification
IdentityRP-HPLC, ESI-MSConsistent with reference standard;

Measured MW ±2 Da

Chromatographic Purity (RP-HPLC, Area %)RP-HPLC ≥99.0%
Largest Single Unknown ImpurityRP-HPLC≤0.50%
Total Related ImpuritiesRP-HPLC≤2.0%
Peptide Assay ContentHPLC Quantitation / Potentiometric Titration98.0% ~ 102.0%
Water ContentKarl Fischer Titration≤1.0%
Residual TFA / AcetateIon Chromatography≤0.5%
Endotoxin (LAL, USP <85>)Turbidimetric LAL Method≤10EU/mg
Heavy Metals (Pb, As, Cd, Hg)ICP-MSEach ≤10 ppm
Residual Organic SolventsGCComply with ICH Q3C requirements
Amino Acid Composition AnalysisAmino Acid AnalyzerWithin ±10% theoretical stoichiometry

4. Storage & Stability

Lyophilized Solid Powder

  • Long-term storage: ≤ -80 ℃, sealed, dry, protected from light — Shelf life: 24 months
  • Medium-term storage: -20 ℃, sealed & desiccated — Shelf life: 12 months
  • Important: Avoid repeated freeze-thaw cycles

Reconstituted Aqueous Stock Solution

  • -80 ℃: Stable up to 6 months
  • -20 ℃: Stable up to 1 month
  • Do not store aqueous solution at 4 ℃ or room temperature for extended periods

5. Stock Solution Preparation Guidance

Molecular Weight = 1419.54

  • 1 mM solution: 1.420 mg BPC-157 per 1 mL solvent
  • Recommended solvent: Sterile purified water or pH7.0–7.4 PBS buffer

    Suggestion: Prepare fresh working solution for in vivo experiments.

6. Safety & Handling Notes

  • This synthetic peptide may irritate skin, eyes and respiratory tract.
  • Required PPE: Lab coat, nitrile gloves, safety goggles.
  • Prevent inhalation of powder dust and direct skin contact.
  • Waste shall be disposed as chemical waste following local regulations.
  • Disclaimer: THIS MATERIAL IS FOR LABORATORY RESEARCH ONLY. Not approved for human administration, clinical use or veterinary medication.

7. RP-HPLC Analytical Conditions

  • Column: C18 analytical column (250×4.6 mm, 5 μm)
  • Mobile Phase A: 0.1% TFA in Water
  • Mobile Phase B: 0.1% TFA in Acetonitrile
  • Detection wavelength: 220 nm / 280 nm
  • Flow rate: 1.0 mL/min
  • Column temperature: 30 ℃

**End of Document**

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