GHK-Cu Complete Usage Guide

1.What Is GHK–Cu?

GHK‑Cu is a complex of the tripeptide GHK (glycyl‑histidyl‑lysine) and copper ions.

Discovered in 1973 by Dr. Loren Pickart, it naturally occurs in human plasma, saliva, and urine.

Levels drop by more than half after age 60, matching reduced tissue repair capacity.

It works by:

• Promoting collagen & elastin production
• Supporting angiogenesis(new blood vessels)
• Reducing inflammation & oxidative damage
• Accelerating wound healing and tissue remodeling

2.Key Benefits

• Skin firming, anti‑wrinkle, and anti‑aging
• Improve skin thickness, elasticity, and barrier function
• Reduce sun damage, dark spots, and rough texture
• Support hair growth & reduce hair loss
• Promote tissue repair, wound healing, and recovery
• Mild analgesic (pain relief) and anti‑anxiety effects in research

3.Official Dosing & Reconstitution (From Your PDF)

Standard Official Dose

• Dose: 1 mg – 2 mg daily
• Route: Subcutaneous (SubQ) injection
• Cycle: 30 days on, 14 days off

Reconstitution Instructions (50mg / 75mg / 100mg vials)

• 50 mg vial + 2 mL bacteriostatic water
• 1 mg = 4 units
• 2 mg = 8 units
• 75 mg vial + 2 mL bacteriostatic water
• 1 mg = 3 units
• 2 mg = 5 units
• 100 mg vial + 3 mL bacteriostatic water
• 1 mg = 3 units
• 2 mg = 6 units

Peptide Class

Copper‑binding tripeptide

4.Full Clinical Dosing Table (Research + Clinical Use)

5.Administration

• Injection type: Subcutaneous (abdomen, thigh, upper arm fat tissue)
• Reconstitution: Use bacteriostatic wateronly
• Sterile techniquerequired to avoid infection

6.Safety & Side Effects

Generally safe

• Naturally occurring
• Non‑toxic at clinical doses
• Well‑tolerated in studies

Possible mild side effects

• Redness, itching, irritation at injection site
• Temporary fatigue
• Rare: mild copper‑like stomach upset

Warnings

• Not for active or suspected cancer(may promote angiogenesis)
• Avoid in Wilson’s disease(copper buildup disorder)
• Not for under 18, pregnancy, or breastfeeding(insufficient data)
• Risk of “copper uglies” with overuse(temporary collagen breakdown)

7.Results Timeline

• Week 1–2: Better hydration, less redness, smoother skin
• 1–2 months: Fewer fine lines, improved elasticity
• 3–6 months: Tighter skin, reduced spots, firmer texture
• Hair: Visible thickness improvement in 2–3 months

8.DISCLAIMER

This dosing guide provides general information only.

It is not a replacement for professional medical advice.

Dosing must be individualized by a licensed physician.